Najwa Aiad Saad Al-Aqili

Rabeaa Mohammed Saleh

Abstract :

This study investigated the relationship between serum prolactin (PRL) levels and other pituitary hormones-Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), and Thyroid-Stimulating Hormone (TSH) and their impact on female fertility. The study included 60 randomly selected women attending the outpatient gynecology and obstetrics clinic in Al-Marj city, eastern Libya, aged between 14 and 50 years, during the period from November 2024 to December 2024. Results showed elevated PRL levels in the 14–24 age group, with levels decreasing with age. FSH and LH levels increased with age, especially after menopause. TSH levels varied and were positively correlated with PRL in certain cases. An inverse relationship was found between PRL and both FSH and LH, indicating PRL’s influence on fertility by affecting the hormonal balance responsible for menstruation and ovulation. The study highlights the regulatory interplay between PRL, FSH, LH, and TSH, emphasizing the importance of hormonal evaluation in fertility assessment.

Study Problem: The lack of awareness among most women regarding the risks associated with elevated prolactin levels (hyperprolactinemia) and its effect on fertility, as well as the lack of routine monitoring.